Orlando, Florida – for decades, the inserts of patients for oral isotretinoin, the golden treatment standard for severe acne, have advised that people avoid undergoing facial excavation treatments, including at least 6 months after 6 -month -olds.
Tips have arose from concerns that this can increase the risk of scar and delayed healing if laser was used in combination. Dermatologists, in turn, are concerned about the legal risk of ignoring laser tips and use earlier. But many have come to see to wait as unnecessary.
In 2017, the US Dermatological Surgery Society published a consent statement In conclusion, there is insufficient evidence to support the packaging composition and that non -gradient lasers and fractional devices can be safely used in patients receiving isotretinoin or recently stopped treatment. Further, in 2024 randomized future Split-face test He found that concomitant treatment with isotretinoin and fractional abstract carbon dioxide laser was associated with better scars than when laser treatment was delayed up to 6 months after isotretinoin discontinuation.
At the recent annual meeting of the US company for Medicine and Surgery (ASLMS) 2025, presenters provided additional information on safe simultaneous use of lasers and drugs, including isotretinoin. It is important that studies have been enrolled people with darker skin tones, for which laser processes have particular concerns about hyperchromatosis, retreat or deterioration of scars.
Timothy Holland, makeDermatology inhabited at the San Diego Naval Medical Center presented a small case study of three patients with Fitzpatrick IV-VI skin types, which received between 60 mg and 80 mg of isotretinoin a day. Everyone underwent a series of four laser he treatments for acne scars for 4 months during treatment. Laser treatment was only administered on one side of the face using a 1565 nm non-defining fractional laser.
“We used conservative treatment arrangements and they have increased in a gradual approach to every month of follow -up,” the Netherlands told the conference. The primary endpoints were new or deterioration of the over-communication and the deterioration of existing scars.
“Our results were great,” the Netherlands said. “We did not see side effects on the side treated compared to the control side and each patient describes at least some improvement over isotretinoin.”
In an interview with Medscape Medical NewsThe Netherlands explained that the results not only add elements to elements that support simultaneous isotretinoin and laser treatment to color patients, but also help to treat a timing problem often observed in the army. “We have patients with an active service who may be at this duty station for one year, but they will develop next year and may not have access to a dermatologist. They would like to start treating their acne while they can,” he said.
Commenting on the conference on the study of the Netherlands, David GoldbergMD, JD, of the Icahn Medical School on Mount Sinai in New York, said the results were reflected. “Dr. Khatri showed us almost 20 years ago that you can safely use a [810-nm diode] Laser removal system within one month of isotretinoin cessation or even when it was in it, “he said, referring to one Book 2006 by Khalil Khatri, MD, a dermatologist based on New Hamsire. “The evidence exists for all these non -formative devices, which is really what [Holland] showed. ”
Goldberg, who is also a lawyer, warned that in the event of complications leading to lawsuit, plaintiff’s lawyers can report the inserts of the isotretinoin package. However, he said: “You will have no problem finding an expert who will defend the fact that you used such a device because everyone is doing this.”
At the conference, Goldberg also presented elements that supported the simultaneous use of a laser-in-case treatment, a 1726 Nm laser designed to heal acne-people taking medication for moderate to severe acne. In this study, 125 patients aged 15-35 (60% of women) with fitzpatrick types IV received three laser remedies at monthly followed by 2 years follow-up visits.
Participants who were in acne treatment before the study had to maintain the same dose and routine for the first two treatments. Three received isotretinoin. Other shapes of participants included oral antibiotics, steroids and/or local treatments. There were no unexpected side effects from laser treatments among people who took drugs or combinations of drugs, Goldberg said.
The Netherlands had no financial notices. Goldberg revealed a conventional investigation into Cutera, a 1726 Nm laser manufacturer used in his study.
