Is there a connection between the gum’s disease and Alzheimer’s disease?
In an analysis of 2020 led by the National Institute of Aging (NIA), scientists suggest that gum -causing bacteria are also linked to the development of Alzheimer’s disease and dementia, especially vascular dementia. The results were reported to the Journal of Alzheimer’s magazine.
A 2016 study was conducted jointly by the University of Southampton and Kings College, London, also reported a relationship between gum disease and the highest cognitive reduction in people with early stages of Alzheimer’s disease.
Professor Clive Holmes, a senior writer from the University of Southampton, said in his conclusion: “These are very interesting results based on previous work we have done, showing that chronic inflammatory conditions have a detrimental effect on the progression of option for the risk of Alzheimer’s. “
Periodontitis or gum disease is common in older people and is probably more common in Alzheimer’s disease due to the reduced ability to take care of oral hygiene as the disease progresses. Increased levels of antibodies in periodontal bacteria are associated with elevated levels of inflammatory molecules in other parts of the body, which in turn have been linked to higher rates of cognitive reduction in Alzheimer’s disease. In Southampton’s study, researchers have set that they determine whether periodontitis is associated with increased severity of the disease and/or by subsequent escalation of the cognitive decline of people who develop the disease.
Porphyromonas gingivalis is the most common guilty of gum disease. Studies indicate that beta-amyloid protein slabs, an important feature of Alzheimer’s disease, can be produced in response to this infection.
NIA analysis revealed that older adults with signs of disease and oral infections at the onset were more likely to develop Alzheimer’s during the study period. Among these 65 years and over, both Alzheimer’s diagnoses and deaths have been associated with antibodies against the P. Gingivalis oral bacterium, which can accumulate with other bacteria such as Campylobacter Rectus and Prevotella melaninogenica to further increase these risk.
Researchers note that the Southampton study should be reproduced with a larger group, as the exact medium by which gum disease can be linked to cognitive decline is not fully transparent and other factors may play in the cognitive decline in parallel with oral health.
Gum disease is an infection caused by bacteria that enter under the gum tissue. Bacteria toxins and body response to infection can begin to destroy the gums and bones that support the teeth.
According to the national health and nutrition examination study, about 42% of US adults aged 30 and over have periodontitis, with about 7.8% of adults having severe periodontitis. The American Dental Union is the practice of good oral hygiene daily, including brushing at least twice a day, using toothpaste, thread, eats a healthy diet that restricts sugary drinks and snacks and visiting a dentist regularly. The treatment for periodontitis includes professional cleaning, gum transplantation, laser gum surgery and root planet.
