CoQ10 in dentistry: Practical applications
CoQ10 it is found in several forms, including oral supplements, topical gels, and mouthwashes. Current CoQ10 The gel can be applied directly to the gums, where it is absorbed into the tissues and offers local anti-inflammatory and antioxidant benefits. Studies have shown that applying CoQ10 Gel in periodontal pockets can help reduce gum inflammation, promote faster healing, and provide better results.7,8
Using CoQ10 with hyaluronic acid as a gel supplement was shown to be effective in the treatment of chronic periodontal disease in 2016.9 Dental professionals could even recommend CoQ10 supplementation as part of a comprehensive periodontal treatment plan, with clinical evidence showing that CoQ10 supplementation at doses of 200 mg daily or higher for prolonged periods is safe, well tolerated, and results in a significant increase in plasma CoQ10 flat. This dose also effectively reduces oxidative stress and reduces cardiovascular mortality.10
I am very optimistic about products that support the oral microbiome and enhance its health without disturbing its delicate balance. Consider making tonight’s dinner a piece of oily fish, with a spinach salad, nuts, seeds and avocado to boost your CoQ10. Good appetite!
References
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3. Rasoolzadeh EA, Shidfar F, Rasoolzadeh RA, Hezaveh ZS. The effect of coenzyme Q10 on periodontitis: systematic review and meta-analysis of clinical trials. J Evid Based Dent Pract. 2022;22(2):101710. doi:10.1016/j.jebdp.2022.101710
4. Manthena S, Rao MV, Penubolu LP, Putcha M, Harsha AV. Effectiveness of oral CoQ10 supplementation as an adjunct to scaling and root planing in improving periodontal health. J Clin Diagn Res. 2015;9(8):ZC26-ZC28. doi:10.7860/JCDR/2015/13486.6291
5. Schmelzer C, Lindner I, Rimbach G, Niklowitz P, Menke T, Döring F. Functions of coenzyme Q10 in inflammation and gene expression. Bioagents. 2008? 32 (1-4): 179-183. doi:10.1002/biof.5520320121
6. Nakamura R, Littarru GP, Folkers K, et al. The effects of coenzyme Q10 on periodontal tissue regeneration. Proc Nat Acad Sci. 1974, 71(4):1456-1460. https://www.pnas.org/doi/pdf/10.1073/pnas.71.4.1456
7. Hanioka T, Tanaka M, Ojima M, Shizukuishi S, Folkers K. Effect of topical application of coenzyme Q10 on adult periodontitis. Mol Aspects Med. 1994, 15 Suppl:s241-s248. doi:10.1016/0098-2997(94)90034-5
8. Raut CP, Sethi KS, Kohale B, Mamajiwala A, Warang A. Subgingivally administered coenzyme Q10 in the treatment of chronic periodontitis among smokers: a randomized controlled clinical trial. J Oral Biol Craniofac Res. 2019? 9 (2): 204-208. doi:10.1016/j.jobcr.2018.05.005
9. Sharma V, Gupta R, Dahiya P, Kumar. Comparative evaluation of coenzyme Q 10-based gel and 0.8% hyaluronic acid gel in the treatment of chronic periodontitis. J Indian Soc Periodont. 2016? 20 (4): 374-380. doi:10.4103/0972-124X.183097
10. Rabanal-Ruiz Y, Llanos-González E, Alcain FJ. The use of coenzyme Q10 in cardiovascular diseases. Antioxidants (Basel). 2021? 10(5):755. doi: 10.3390/antiox10050755
